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Rheumatoid nodules: a narrative review of...
Journal article

Rheumatoid nodules: a narrative review of histopathological progression and diagnostic consideration

Abstract

Rheumatoid nodules (RNs) are the most common extra-articular manifestation of rheumatoid arthritis and are also seen in patients with other autoimmune and inflammatory diseases. The development of RNs includes histopathological stages of acute unspecified inflammation, granulomatous inflammation with no or minimal necrosis, necrobiotic granulomas typically with central fibrinoid necrosis surrounded by palisading epithelioid macrophages and …

Authors

Fareez F; Moodley J; Popovic S; Lu J-Q

Journal

Clinical Rheumatology, Vol. 42, No. 7, pp. 1753–1765

Publisher

Springer Nature

Publication Date

7 2023

DOI

10.1007/s10067-023-06589-6

ISSN

0770-3198