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Effect of sample preparation techniques on the...
Journal article

Effect of sample preparation techniques on the concentrations and distributions of elements in biological tissues using µSRXRF: a comparative study

Abstract

Routine tissue sample preparation using chemical fixatives is known to preserve the morphology of the tissue being studied. A competitive method, cryofixation followed by freeze drying, involves no chemical agents and maintains the biological function of the tissue. The possible effects of both sample preparation techniques in terms of the distribution of bio-metals (calcium (Ca), copper (Cu) zinc (Zn), and iron (Fe) specifically) in human skin …

Authors

Al-Ebraheem A; Dao E; Desouza E; Li C; Wainman BC; McNeill FE; Farquharson MJ

Journal

Physiological Measurement, Vol. 36, No. 3, pp. n51–n60

Publisher

IOP Publishing

Publication Date

March 1, 2015

DOI

10.1088/0967-3334/36/3/n51

ISSN

0967-3334