Journal article
Combined Histological and Endoscopic Endpoints at Post-induction Lack Additional Prognostic Value Compared with Endoscopic Improvement Alone in Ulcerative Colitis: A Post hoc Analysis of the VARSITY study
Abstract
BACKGROUND AND AIMS: Evaluating histological outcomes in ulcerative colitis [UC] has become common in recent clinical trials. In this study, we explored the additional value of the combined endpoint of histo-endoscopic mucosal improvement [HEMI] compared with endoscopic improvement [EI] at post-induction [Week 14] and post-maintenance [1 year].
METHODS: This post hoc analysis included 620 UC participants with available data from the VARSITY …
Authors
Wong ECL; Dulai PS; Hasan B; Marshall JK; Reinisch W; Narula N
Journal
Journal of Crohn's and Colitis, Vol. 17, No. 7, pp. 1114–1121
Publisher
Oxford University Press (OUP)
Publication Date
July 5, 2023
DOI
10.1093/ecco-jcc/jjad033
ISSN
1197-4982