Genetic Analysis Workshop 18: Methods and strategies for analyzing human sequence and phenotype data in members of extended pedigrees Academic Article uri icon

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  • Genetic Analysis Workshop 18 provided a platform for developing and evaluating statistical methods to analyze whole-genome sequence data from a pedigree-based sample. In this article we present an overview of the data sets and the contributions that analyzed these data. The family data, donated by the Type 2 Diabetes Genetic Exploration by Next-Generation Sequencing in Ethnic Samples Consortium, included sequence-level genotypes based on sequencing and imputation, genome-wide association genotypes from prior genotyping arrays, and phenotypes from longitudinal assessments. The contributions from individual research groups were extensively discussed before, during, and after the workshop in theme-based discussion groups before being submitted for publication.


  • Bickeböller, Heike
  • Bailey, Julia N
  • Beyene, Joseph
  • Cantor, Rita M
  • Cordell, Heather J
  • Culverhouse, Robert C
  • Engelman, Corinne D
  • Fardo, David W
  • Ghosh, Saurabh
  • König, Inke R
  • Lorenzo Bermejo, Justo
  • Melton, Phillip E
  • Santorico, Stephanie A
  • Satten, Glen A
  • Sun, Lei
  • Tintle, Nathan L
  • Ziegler, Andreas
  • MacCluer, Jean W
  • Almasy, Laura

publication date

  • June 2014