Journal article
EFFECTS OF LIGHT BEAM SIZE ON FLUENCE DISTRIBUTION AND DEPTH OF NECROSIS IN SUPERFICIALLY APPLIED PHOTODYNAMIC THERAPY OF NORMAL RAT BRAIN
Abstract
The light fluence distributions of 632.8 nm light incident on the exposed surface of normal rat brain in vivo have been measured using an interstitial, stereotactically-mounted optical fiber detector with isotropic response. The dependence of the relative fluence rate on depth and the spatial distribution of fluence were compared for incident beam diameters of 3 and 5 mm. The fluence rate at depth of 1-6 mm along the optical axis within the …
Authors
Chen Q; Wilson BC; Dereski MO; Patterson MS; Chopp M; Hetzel FW
Journal
Photochemistry and Photobiology, Vol. 56, No. 3, pp. 379–384
Publisher
Wiley
Publication Date
September 1992
DOI
10.1111/j.1751-1097.1992.tb02174.x
ISSN
0031-8655