Journal article
The use of spatially resolved fluorescence and reflectance to determine interface depth in layered fluorophore distributions
Abstract
The possibility of using spatially resolved fluorescence and reflectance measurements to recover tissue optical properties, fluorophore concentration and the thickness of a superficial layer in a two-layer geometry was investigated. A diffusion theory model was used to fit reflectance and fluorescence data generated using Monte Carlo simulations or experimentally obtained using tissue-simulating phantoms. Initial analysis fitting diffusion …
Authors
Stasic D; Farrell TJ; Patterson MS
Journal
Physics in Medicine and Biology, Vol. 48, No. 21, pp. 3459–3474
Publisher
IOP Publishing
Publication Date
November 7, 2003
DOI
10.1088/0031-9155/48/21/001
ISSN
0031-9155