Determination of the optical properties of tissue-simulating phantoms from interstitial frequency domain measurements of relative fluence and phase difference.

We estimated the absorption and reduced scattering coefficients of tissue-simulating phantoms from interstitial measurements of the phase difference and relative amplitude signals at two distances from a sinusoidally modulated isotropic source. It was found that absorption and reduced scattering coefficients can be recovered within 10% and slightly over 10% respectively, using either the data collected by two detectors 3mm apart or by two …