Journal article
Measurement of Intracellular Oxygen Concentration During Photodynamic Therapy in vitro
Abstract
A technique is introduced that monitors the depletion of intracellular ground state oxygen concentration ([(3)O(2)]) during photodynamic therapy of Mat-LyLu cell monolayers and cell suspensions. The photosensitizer Pd(II) meso-tetra(4-carboxyphenyl)porphine (PdT790) is used to manipulate and indicate intracellular [(3)O(2)] in both of the in vitro models. The Stern-Volmer relationship for PdT790 phosphorescence was characterized in suspensions …
Authors
Weston MA; Patterson MS
Journal
Photochemistry and Photobiology, Vol. 90, No. 4, pp. 878–888
Publisher
Wiley
Publication Date
July 2014
DOI
10.1111/php.12256
ISSN
0031-8655