Peripheral sensory input directs apomorphine-induced circling in rats

In normal rats administered apomorphine, bandaging of one side of the head produces circling towards the sensory intact (opposite) side. A sensory imbalance can, therefore, determine the direction of apomorphine-induced circling. This suggests that one way in which central dopaminergic activity may exert its effects on behaviour, including circling, is by altering the balance of sensory input.