Journal article
Association of Altered Whole-Body Metabolism with Locomotor Sensitization Induced by Quinpirole
Abstract
Repeated exposure to drugs classed as psychostimulants can produce behavioral sensitization, defined as augmented motor responses to fixed doses of such compounds. For example, chronic treatment of rats with the dopamine D2/D3 agonist quinpirole increases the locomotor response to this drug to levels that are several times higher than after acute treatment. To determine if such enhanced activity is associated with changes in energy metabolism, …
Authors
Coscina DV; Currie PJ; Szechtman H
Journal
Physiology & Behavior, Vol. 63, No. 5, pp. 755–761
Publisher
Elsevier
Publication Date
March 1998
DOI
10.1016/s0031-9384(97)00531-3
ISSN
0031-9384