Platform, Basket, and Umbrella Trial Designs: Stakeholder Perspectives of Novel Therapeutics

Advancements in genomic and precision medicine have changed the way oncology clinical trials are designed. Compared to the traditional single tumour-based trial, master protocols, which are often classified as basket, umbrella, or platform trials, conduct studies on multiple subgroups under a single overarching protocol. This paper presents the perspectives of patients, clinicians, public payers, private payers, and industry, which were discussed during the third webinar. The discussion section of this paper summarizes the major points raised by the presenters, as well as questions from the audience and answers from the presenters.