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Does the number of 6-monthly adjuvant zoledronate...
Journal article

Does the number of 6-monthly adjuvant zoledronate infusions received affect treatment efficacy for early breast cancer? A sub-study of ABCSG-12

Abstract

BACKGROUND: The widespread adoption of adjuvant bisphosphonate therapy for postmenopausal early breast cancer (EBC) patients was based on results of the Early Breast Cancer Trialist Group (EBCTCG) meta-analysis. Despite multiple regimens evaluated, there was no signal of varying efficacy with type, dose/dose intensity of bisphosphonate administration. We evaluated the effect of early treatment cessation using long-term outcome data from the …

Authors

Beltran-Bless A-A; Clemons MJ; Fesl C; Greil R; Pond GR; Balic M; Vandermeer L; Bjelic-Radisic V; Singer CF; Steger GG

Journal

European Journal of Cancer, Vol. 180, , pp. 108–116

Publisher

Elsevier

Publication Date

February 2023

DOI

10.1016/j.ejca.2022.12.003

ISSN

0959-8049