Journal article
Beneficial effects of creatine, CoQ10, and lipoic acid in mitochondrial disorders
Abstract
Mitochondrial disorders share common cellular consequences: (1) decreased ATP production; (2) increased reliance on alternative anaerobic energy sources; and (3) increased production of reactive oxygen species. The purpose of the present study was to determine the effect of a combination therapy (creatine monohydrate, coenzyme Q(10), and lipoic acid to target the above-mentioned cellular consequences) on several outcome variables using a …
Authors
Rodriguez MC; MacDonald JR; Mahoney DJ; Parise G; Beal MF; Tarnopolsky MA
Journal
Muscle & Nerve, Vol. 35, No. 2, pp. 235–242
Publisher
Wiley
Publication Date
2 2007
DOI
10.1002/mus.20688
ISSN
0148-639X