Methodological Issues in Evidence-Based Evaluation of Treatment for Recurrent Miscarriage

The philosophy of employing evidence from valid and current studies to assist in making clinical decisions is now widely acknowledged as desirable for improving the quality of care provided to patients. The principles of this evidence-based approach to health care management involve searching the literature for studies and critically appraising them to answer clearly defined and focused questions generated from encounters with patients presenting with their clinical problems. This approach is necessary to guide management in obstetrics and gynecology, including the subspecialty of infertility dealing with the problem of recurrent miscarriage.