A variable-temperature 13C NMR study of (η5-C5H5)2Mo2(CO)4 complexes of chiral alkynes derived from a terpene or a hormonal steroid: interconversion of diastereomers via exchange of terminal and semi-bridging carbonyls Academic Article uri icon

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abstract

  • The reaction of (C5H5)2Mo2(CO)4 with the steroidal hormone 11β-(4-dimethylaminophenyl)-17β-hydroxy-17α-(1-propynyl)-estra-4,9-dien-3-one (RU 38486) or with propynylborneol yields in each case a chiral cluster that exhibits two cyclopentadienyl resonances in both the 1H and 13C NMR regimes. At low temperature the interconversion of diastereomers arising from the different orientations of the semi-bridging carbonyl ligand can be slowed on the NMR time scale. The barrier to diastereomer interchange has been determined for the terpenoid cluster and the mechanism of this process is discussed.

publication date

  • June 1, 1992