Journal article
The Relationship between Genotype and Exercise Tolerance in Children with Cystic Fibrosis
Abstract
The relationship between fitness and genotype in children with cystic fibrosis (CF) and at least one copy of the DeltaF508 mutation was examined. Genotype was classified according to the second CF mutation. Fitness was measured by peak aerobic capacity (using a modified Bruce protocol during treadmill exercise) and anaerobic power (using the Wingate test on a cycle ergometer). The class of cystic fibrosis transmembrane regulator proteins (CFTR) …
Authors
SELVADURAI HC; McKAY KO; BLIMKIE CJ; COOPER PJ; MELLIS CM; VAN ASPEREN PP
Journal
American Journal of Respiratory and Critical Care Medicine, Vol. 165, No. 6, pp. 762–765
Publisher
American Thoracic Society
Publication Date
March 15, 2002
DOI
10.1164/ajrccm.165.6.2104036
ISSN
1073-449X