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Precision oncology using ex vivo technology: a...
Journal article

Precision oncology using ex vivo technology: a step towards individualised cancer care?

Abstract

Despite advances in cancer genomics and the increased use of genomic medicine, metastatic cancer is still mostly an incurable and fatal disease. With diminishing returns from traditional drug discovery strategies, and high clinical failure rates, more emphasis is being placed on alternative drug discovery platforms, such as ex vivo approaches. Ex vivo approaches aim to embed biological relevance and inter-patient variability at an earlier stage …

Authors

Williams ST; Wells G; Conroy S; Gagg H; Allen R; Rominiyi O; Helleday T; Hullock K; Pennington CEW; Rantala J

Journal

Expert Reviews in Molecular Medicine, Vol. 24, ,

Publisher

Cambridge University Press (CUP)

Publication Date

2022

DOI

10.1017/erm.2022.32

ISSN

1462-3994

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