Journal article
Mammalian Sperm Proteins Are Rapidly Evolving: Evidence of Positive Selection in Functionally Diverse Genes
Abstract
A growing number of genes involved in sex and reproduction have been demonstrated to be rapidly evolving. Here, we show that genes expressed solely in spermatozoa represent a highly diverged subset among mouse and human tissue-specific orthologs. The average rate of nonsynonymous substitutions per site (K(a)) is significantly higher in sperm proteins (mean K(a) = 0.18; N = 35) than in proteins expressed specifically in all other tissues (mean …
Authors
Torgerson DG; Kulathinal RJ; Singh RS
Journal
Molecular Biology and Evolution, Vol. 19, No. 11, pp. 1973–1980
Publisher
Oxford University Press (OUP)
Publication Date
November 1, 2002
DOI
10.1093/oxfordjournals.molbev.a004021
ISSN
0737-4038