SELECTION FOR MALATHION-RESISTANCE INDROSOPHILA MELANOGASTER Journal Articles

abstract

• Results from a long-term selection experiment for malathion-resistance in Drosophila melanogaster are described. A pooled population of 40 locally-caught, iso-female lines was exposed to increasing concentrations of malathion in the food at both a high selection intensity (MH) and a lower intensity (ML). The response was consistent with a polygenic system. Both adult and larval resistance increased in parallel. Changes in the dose-response curve of adults could be approximately described by a dose-modification factor. Larval resistance was more complex; both selected populations showed a maternal effect which could not be explained by sex-linked genes. Larval resistance in the selected populations behaved as a co-dominant trait with respect to the susceptible controls. Adult resistance was dominant in the ML and co-dominant in the MH population, suggesting that different genes conferring resistance were selected. The selection procedure also produced a developmental delay in both populations, dependent on malathion concentration, but present even in its absence.

authors

• Singh, Rama Shankar
• Morton, Richard Alan

status

• published 

publication date

• June 1, 1981

has subject area

• 0604 Genetics (FoR)
• 0703 Crop and Pasture Production (FoR)
• 1001 Agricultural Biotechnology (FoR)
• Animals (MeSH)
• Dose-Response Relationship, Drug (MeSH)
• Drosophila melanogaster (MeSH)
• Extrachromosomal Inheritance (MeSH)
• Female (MeSH)
• Genes, Dominant (MeSH)
• Insecticide Resistance (MeSH)
• Malathion (MeSH)
• Male (MeSH)
• Plant Biology & Botany (Science Metrix)

published in

• Genome  Journal

keywords

• Animals
• Dose-Response Relationship, Drug
• Drosophila melanogaster
• Extrachromosomal Inheritance
• Female
• Genes, Dominant
• Insecticide Resistance
• Malathion
• Male

Digital Object Identifier (DOI)

• 10.1139/g81-038

PubMed ID

• 6794889

start page

• 355

end page

• 369

volume

• 23

issue

• 2