MACE in the Race: A Canadian Perspective on Major Adverse Cardiac Events (MACE) During Running

The recent tragic deaths of two fit and healthy Canadian physicians during running have shocked the whole Canadian medical community. In order to prevent such loss of precious human lives, the paradox of dying during a life-prolonging activity begets further contemplation and investigation on whether we have been missing something in assessing the risk of major cardiovascular adverse events (MACE) in fit individuals during long-distance running. Additionally, knowing the potential, yet the rare fatal risk of running, physicians are obliged to disclose that fatal risk while prescribing exercise to their patients according to the Supreme Court of Canada Ruling. Further research is urgently needed.