Topical therapy with negative allosteric modulators of the calcium-sensing receptor (calcilytics) for the management of asthma: the beginning of a new era? Journal Articles uri icon

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abstract

  • In this review article we present the evidence to date supporting the role of the calcium-sensing receptor (CaSR) as a key, pluripotential molecular trigger for asthma and speculate on the likely benefits of topical therapy of asthma with negative allosteric modulators of the CaSR: calcilytics.

authors

  • Riccardi, Daniela
  • Ward, Jeremy PT
  • Yarova, Polina L
  • Janssen, Luke Jeffrey
  • Lee, Tak Hong
  • Ying, Sun
  • Corrigan, Chris J

publication date

  • August 2022