Journal article
Attenuation of ethanol tolerance by a novel stimulus
Abstract
A Pavlovian conditioning model of tolerance emphasizes that an association between predrug cues and the systemic effects of the drug contributes to tolerance. On the basis of this model, established tolerance should be attenuated by “external inhibition,” i.e., by presentation of a novel, extraneous stimulus. This prediction was evaluated in the present experiment. Rats that were so tolerant to the hypothermic effect of ethanol that they …
Authors
Siegel S; Sdao-Jarvie K
Journal
Psychopharmacology, Vol. 88, No. 2, pp. 258–261
Publisher
Springer Nature
Publication Date
6 1986
DOI
10.1007/bf00652251
ISSN
0033-3158