Journal article
Structural polymorphism of the four-repeat Oxytricha nova telomeric DNA sequences
Abstract
G-quadruplexes are four-stranded nucleic acid complexes that exhibit a great deal of polymorphism. Recently a group described the polymorphism exhibited by the four-repeat of the Oxytricha nova telomeric sequences (Lee, J.Y., Yoon, J., Kihm, H.W., Kim, D.S., Biochemistry 2008, 47, 3389-3396). In this study we evaluated the effects of G-tract and loop lengths on this behaviour using circular dichroism (CD) and gel electrophoresis. The largest …
Authors
Abu-Ghazalah RM; Macgregor RB
Journal
Biophysical Chemistry, Vol. 141, No. 2-3, pp. 180–185
Publisher
Elsevier
Publication Date
May 2009
DOI
10.1016/j.bpc.2009.01.013
ISSN
0301-4622