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A Unified Model of Codon Reassignment in...
Journal article

A Unified Model of Codon Reassignment in Alternative Genetic Codes

Abstract

Many modified genetic codes are found in specific genomes in which one or more codons have been reassigned to a different amino acid from that in the canonical code. We present a new framework for codon reassignment that incorporates two previously proposed mechanisms (codon disappearance and ambiguous intermediate) and introduces two further mechanisms (unassigned codon and compensatory change). Our theory is based on the observation that …

Authors

Sengupta S; Higgs PG

Journal

Genetics, Vol. 170, No. 2, pp. 831–840

Publisher

Oxford University Press (OUP)

Publication Date

June 1, 2005

DOI

10.1534/genetics.104.037887

ISSN

0016-6731