Acetated Ringer's Solution Containing Mg2+ - Maintained Serum Ionized Mg Consistently Throughout Long Elective Abdominal Surgery

The patients, scheduled for more than 6 hours of elective abdominal surgery, were randomized to two groups. Sixteen patients in Veen F (V) group received Mg2+ - free acetated Ringer's solution. Fourteen patients in Physio140 (P) group received acetated Ringer's solution containing 1mmol·l -1 Mg2+. In the V group, ionized magnesium concentrations were gradually decreased, but the reduction in ionized magnesium concentrations was significantly inhibited in the P group. In the P group, the ionized chloride concentration was significantly increased 6 hours after the start of the surgery. In the V group, the reduction ratio of ionized magnesium from start to end of anesthesia was well-correlated to the volume of fluid infusion, not to the volume of blood loss, transfusion, or urine. The acetated Ringer's solution containing 1mmol·l -1 Mg2+ is useful to inhibit the decrease in ionized magnesium concentrations during long (over 6 hours) elective abdominal surgery.