Examining the factor structure and discriminative utility of the Infant Behavior Questionnaire–Revised in infant siblings of autistic children Academic Article uri icon

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abstract

  • Using the Infant Behavior Questionnaire-Revised in a longitudinal sample of infant siblings of autistic children (HR; n = 427, 171 female, 83.4% White) and a comparison group of low-risk controls (LR, n = 200, 86 female, 81.5% White), collected between 2007 and 2017, this study identified an invariant factor structure of temperament traits across groups at 6 and 12 months. Second, after partitioning the groups by familial risk and diagnostic outcome at 24 months, results reveal an endophenotypic pattern of Positive Emotionality at both 6 and 12 months, (HR-autism spectrum disorder [ASD] < HR-no-ASD < LR). Third, increased 'Duration of Orienting' at 12 months was associated with lower scores on the 24-month developmental outcomes in HR infants. These findings may augment efforts for early identification of ASD.

authors

  • Sung, Sooyeon
  • Fenoglio, Angela
  • Wolff, Jason J
  • Schultz, Robert T
  • Botteron, Kelly N
  • Dager, Stephen R
  • Estes, Annette M
  • Hazlett, Heather C
  • Zwaigenbaum, Lonnie
  • Piven, Joseph
  • Elison, Jed T
  • Piven, J
  • Hazlett, HC
  • Chappell, C
  • Dager, S
  • Estes, A
  • Shaw, D
  • Botteron, K
  • McKinstry, R
  • Constantino, J
  • Pruett, J
  • Schultz, R
  • Pandey, J
  • Zwaigenbaum, L
  • Elison, JT
  • Wolff, JJ
  • Evans, AC
  • Collins, DL
  • Pike, GB
  • Fonov, V
  • Kostopoulos, P
  • Das, S
  • MacIntyre, L
  • Gerig, G
  • Styner, M
  • Gu, H

publication date

  • September 2022