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A Colloidal Stability Assay Suitable for...
Journal article

A Colloidal Stability Assay Suitable for High-Throughput Screening

Abstract

A library of 32 polystyrene copolymer latexes, with diameters ranging between 53 and 387 nm, was used to develop and demonstrate a high-throughput assay using a 96-well microplate platform to measure critical coagulation concentrations, a measure of colloidal stability. The most robust assay involved an automated centrifugation-decantation step to remove latex aggregates before absorbance measurements, eliminating aggregate interference with …

Authors

Abarca C; Ali MM; Yang S; Dong X; Pelton RH

Journal

Analytical Chemistry, Vol. 88, No. 5, pp. 2929–2936

Publisher

American Chemical Society (ACS)

Publication Date

March 1, 2016

DOI

10.1021/acs.analchem.5b04915

ISSN

0003-2700