Evaluation of the Performance of a Multiplexed Serological Assay in the Detection of SARS-CoV-2 Infections in a Predominantly Vaccinated Population Academic Article uri icon

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abstract

  • Among a cohort of adult paramedics in Canada, we investigated the performance of nucleocapsid (N) antibody detection (measured with a V-PLEX assay) to identify previous COVID-19 infections and compared differences among vaccinated and unvaccinated. Our data indicate that vaccinated and unvaccinated groups require different thresholds to achieve optimal test performance, especially for detecting COVID-19 within the preceding 9 months.

authors

  • Asamoah-Boaheng, Michael
  • Goldfarb, David
  • Barakauskas, Vilte
  • Kirkham, Tracy L
  • Demers, Paul A
  • Karim, Mohammad Ehsanul
  • Lavoie, Pascal M
  • Marquez, Ana Citlali
  • Jassem, Agatha N
  • Jenneson, Sandra
  • MacDonald, Christopher
  • Grunau, Brian

publication date

  • February 23, 2022