Journal article
Administration of Parenteral Vitamin C in Patients With Severe Infection: Protocol for a Systematic Review and Meta-analysis
Abstract
BACKGROUND: Severe infections are characterized by inflammation and oxidative damage. Ascorbic acid (vitamin C) administration may attenuate oxidative damage and, in turn, reduce vascular endothelial injury in pulmonary and systemic vasculature.
OBJECTIVE: We aim to describe a protocol for a living systematic review that will evaluate the effectiveness and safety of parenteral vitamin C administration in adults with severe infections, including …
Authors
Agarwal A; Basmaji J; Fernando SM; Ge FZ; Xiao Y; Faisal H; Honarmand K; Hylands M; Lau VI; Lewis K
Journal
JMIR Research Protocols, Vol. 11, No. 1,
Publisher
JMIR Publications
DOI
10.2196/33989
ISSN
1929-0748