Journal article
Oxymatrine exerts organ- and tissue-protective effects by regulating inflammation, oxidative stress, apoptosis, and fibrosis: From bench to bedside
Abstract
Oxymatrine is a quinazine alkaloid extracted from Sophora flavescens with various therapeutic effects such as organ- and tissue-protective, anti-inflammatory, anti-cancer, and anti-viral effects. In this review, we summarize the protective effects of oxymatrine on damaged organs and tissues by analyzing both in vivo and in vitro studies. The mechanisms of protective effects of oxymatrine are mainly related to its anti-inflammatory, …
Authors
Lan X; Zhao J; Zhang Y; Chen Y; Liu Y; Xu F
Journal
Pharmacological Research, Vol. 151, ,
Publisher
Elsevier
Publication Date
January 2020
DOI
10.1016/j.phrs.2019.104541
ISSN
1043-6618