The neonatal microbiomein uteroand beyond: perinatal influences and long-term impacts Journal Articles uri icon

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abstract

  • AbstractThe neonatal microbiome offers a valuable model for studying the origins of human health and disease. As the field of metagenomics expands, we also increase our understanding of early life influences on its development. In this review we will describe common techniques used to define and measure the microbiome. We will reviewin uteroinfluences, normal perinatal development, and known risk factors for abnormal neonatal microbiome development. Finally, we will summarize current evidence that links early life microbial impacts on the development of chronic inflammatory diseases, obesity, and atopy.

authors

  • Hill, Lee
  • Sharma, Ruchika
  • Hart, Lara
  • Popov, Jelena
  • Moshkovich, Michal
  • Pai, Nikhil

publication date

  • December 20, 2021