Neonatal abstinence syndrome is a potential cause of low TREC copy number Journal Articles

abstract

• AbstractSevere combined immunodeficiency (SCID) is a rare genetic condition characterized by significant T cell lymphopenia and impaired T cell function. Many jurisdictions use the quantitation of T cell receptor excision circles (TRECs) to screen for SCID in newborns, but false positives may be seen in several conditions. We report 3 newborns with neonatal abstinence syndrome who presented with decreased TREC copy number.

authors

• Adatia, Adil
• Ling, Ling
• Chakraborty, Pranesh
• Brick, Lauren
• Brager, Rae

status

• published 

publication date

• December 2021

has subject area

• 1107 Immunology (FoR)
• Allergy (Science Metrix)

published in

• Allergy, Asthma and Clinical Immunology  Journal

keywords

• Neonatal abstinence syndrome
• Opiates
• Primary immunodeficiency
• SCID
• TRECs

Digital Object Identifier (DOI)

• 10.1186/s13223-021-00617-3

start page

• 115

volume

• 17

issue

• 1