Journal article
Effects of hTERT on genomic instability caused by either metal or radiation or combined exposure
Abstract
Genomic instability is considered to be an important component in carcinogenesis. It can be caused by low-dose exposure to agents, which appear to act through induction of stress-response pathways related to oxidative stress. These agents have been studied mostly in the radiation field but evidence is accumulating that chemicals, especially heavy metals such as Cr (VI), can also act in the same manner. Previous work showed that metal ions could …
Authors
Glaviano A; Mothersill C; Case CP; Rubio MA; Newson R; Lyng F
Journal
Mutagenesis, Vol. 24, No. 1, pp. 25–33
Publisher
Oxford University Press (OUP)
Publication Date
January 2009
DOI
10.1093/mutage/gen048
ISSN
0267-8357