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Renal outcomes and mortality following...
Journal article

Renal outcomes and mortality following hydroxyethyl starch resuscitation of critically ill patients: systematic review and meta-analysis of randomized trials: ATTENTION: The analysis and conclusions of this article are being revised by the authors. This is due to the journal Anesthesia and Analgesia's retraction of a paper by Dr. Joachim Boldt, an author in seven of the studies analyzed in this review. As such, the editors of Open Medicine recommend interpreting this review with extreme caution until Zarychanski et al. publish a new analysis and interpretation in Open Medicine. For more information, see Anesthesia and Analgesia's press release.

Abstract

BACKGROUND: Hydroxyethyl starch (HES) is a type of colloid fluid that is commonly used for volume resuscitation of patients admitted to the intensive care unit. Data regarding the renal consequences of HES are conflicting. PURPOSE: To evaluate the effect of HES solutions on renal outcomes and mortality among critically ill patients requiring acute volume resuscitation.

Authors

Zarychanski R; Turgeon AF; Fergusson DA; Cook DJ; Hébert P; Bagshaw SM; Monsour D; McIntyre L

Journal

Open Medicine, Vol. 3, No. 4, pp. e196–e209

Publication Date

2009

ISSN

1911-2092