Experts has a new look! Let us know what you think of the updates.

Provide feedback
Home
Scholarly Works
A Cross-Platform Metabolomics Comparison...
Journal article

A Cross-Platform Metabolomics Comparison Identifies Serum Metabolite Signatures of Liver Fibrosis Progression in Chronic Hepatitis C Patients

Abstract

Metabolomics offers new insights into disease mechanisms that is enhanced when adopting orthogonal instrumental platforms to expand metabolome coverage, while also reducing false discoveries by independent replication. Herein, we report the first inter-method comparison when using multisegment injection-capillary electrophoresis-mass spectrometry (MSI-CE-MS) and nuclear magnetic resonance (NMR) spectroscopy for characterizing the serum …

Authors

Shanmuganathan M; Sarfaraz MO; Kroezen Z; Philbrick H; Poon R; Don-Wauchope A; Puglia M; Wishart D; Britz-McKibbin P

Journal

Frontiers in Molecular Biosciences, Vol. 8, ,

Publisher

Frontiers

DOI

10.3389/fmolb.2021.676349

ISSN

2296-889X