Journal article
Association between the -455T>C promoter polymorphism of the APOC3gene and the metabolic syndrome in a multi-ethnic sample
Abstract
BackgroundCommon polymorphisms in the promoter of the APOC3 gene have been associated with hypertriglyceridemia and may impact on phenotypic expression of the metabolic syndrome (MetS). The rs7566605 marker, located near the INSIG2 gene, has been found to be associated with obesity, making it also a potential genetic determinant for MetS. The objective of this study is to examine the APOC3 -455T>C and the INSIG2 rs7566605 polymorphisms as …
Authors
Pollex RL; Ban MR; Young TK; Bjerregaard P; Anand SS; Yusuf S; Zinman B; Harris SB; Hanley AJ; Connelly PW
Journal
BMC Medical Genomics, Vol. 8, No. 1,
Publisher
Springer Nature
Publication Date
12 2007
DOI
10.1186/1471-2350-8-80
ISSN
1471-2350