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Maternal nutritional history predicts obesity in...
Journal article

Maternal nutritional history predicts obesity in adult offspring independent of postnatal diet

Abstract

Significant alterations in maternal nutrition may induce long-term metabolic consequences in offspring, in particular obesity and leptin and insulin resistance. Although maternal nutrient deprivation has been well characterized in this context, there is a relative paucity of data on how high fat (HF) nutrition impacts on the subsequent generation. The present study investigated the effects of maternal HF nutrition either throughout the mother's …

Authors

Howie GJ; Sloboda DM; Kamal T; Vickers MH

Journal

The Journal of Physiology, Vol. 587, No. 4, pp. 905–915

Publisher

Wiley

Publication Date

February 15, 2009

DOI

10.1113/jphysiol.2008.163477

ISSN

0022-3751