Lipid peroxidation induced by Clinostomum detruncatum in muscle of the freshwater fish Rhamdia quelen Journal Articles uri icon

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  • The effect of Clinostomum detruncatum metacercaria infection on the activities of the antioxidant enzymes superoxide dismutase and catalase in muscle of the freshwater fish Rhamdia quelen was analyzed. Tert-butyl hydroperoxide-initiated chemiluminescence, a measure of lipid peroxidation, was also investigated. Enzyme activities were similar in infected and uninfected fishes. However, the chemiluminescence was almost 2-fold higher in muscle of infected fishes than in muscle of uninfected ones. These results indicate that parasite infection induces oxidative stress and a higher level of membrane damage in the fish muscle due to an imbalance between pro-oxidants and non-enzymatic antioxidants. Our results suggest that fish response to parasite infection could involve, as in other vertebrates, reactive oxygen intermediates.


  • Belló, ARR
  • Fortes, E
  • Belló-Klein, A
  • Belló, AA
  • Llesuy, SF
  • Robaldo, RB
  • Bianchini, Adalto

publication date

  • 2000