Arterial load and right ventricular-vascular coupling in pulmonary hypertension Academic Article uri icon

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abstract

  • Pulmonary vascular impedance (PVZ) represents the most comprehensive measure of right ventricle (RV) afterload; however, measurement of this variable is complex. We demonstrate that characteristic impedance ( Zc) and a wave reflection coefficient, λ, can be derived from RV pressure waveform analysis. In addition, RV dysfunction in left heart disease is independent of its afterload. The current study provides a platform for future studies to examine the pharmacotherapeutic effects and prognosis of different measures of RV afterload.

authors

  • Oakland, Hannah
  • Joseph, Philip
  • Naeije, Robert
  • Elassal, Ahmed
  • Cullinan, Marjorie
  • Heerdt, Paul M
  • Singh, Inderjit

publication date

  • July 1, 2021