Journal article
Arterial load and right ventricular-vascular coupling in pulmonary hypertension
Abstract
Right ventricular (RV) functional adaptation to afterload determines outcome in pulmonary hypertension (PH). RV afterload is determined by the dynamic interaction between pulmonary vascular resistance (PVR), characteristic impedance (Zc), and wave reflection. Pulmonary vascular impedance (PVZ) represents the most comprehensive measure of RV afterload; however, there is an unmet need for an easier bedside measurement of this complex variable. …
Authors
Oakland H; Joseph P; Naeije R; Elassal A; Cullinan M; Heerdt PM; Singh I
Journal
Journal of Applied Physiology, Vol. 131, No. 1, pp. 424–433
Publisher
American Physiological Society
Publication Date
July 1, 2021
DOI
10.1152/japplphysiol.00204.2021
ISSN
8750-7587