Journal article
Methadone induces testosterone suppression in patients with opioid addiction
Abstract
Sex hormones may have a role in the pathophysiology of substance use disorders, as demonstrated by the association between testosterone and addictive behaviour in opioid dependence. Although opioid use has been found to suppress testosterone levels in men and women, the extent of this effect and how it relates to methadone treatment for opioid dependence is unclear. The present multi-centre cross-sectional study consecutively recruited 231 …
Authors
Bawor M; Dennis BB; Samaan MC; Plater C; Worster A; Varenbut M; Daiter J; Marsh DC; Desai D; Steiner M
Journal
Scientific Reports, Vol. 4, No. 1,
Publisher
Springer Nature
DOI
10.1038/srep06189
ISSN
2045-2322