Journal article
VEGF-A165 augments erythropoietic development from human embryonic stem cells
Abstract
Combinations of hematopoietic cytokines and the ventral mesoderm inducer BMP-4 have recently been shown to augment hematopoietic cell fate of human embryonic stem cells (hESCs) during embryoid body (EB) development. However, factors capable of regulating lineage commitment of hESC-derived hematopoiesis have yet to be reported. Here we show that vascular endothelial growth factor (VEGF-A165) selectively promotes erythropoietic development from …
Authors
Cerdan C; Rouleau A; Bhatia M
Journal
Blood, Vol. 103, No. 7, pp. 2504–2512
Publisher
American Society of Hematology
Publication Date
April 1, 2004
DOI
10.1182/blood-2003-07-2563
ISSN
0006-4971