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Low-dose rivaroxaban plus aspirin in patients with...
Journal article

Low-dose rivaroxaban plus aspirin in patients with polypharmacy and multimorbidity: an analysis from the COMPASS trial

Abstract

AIMS: To analyse whether the benefits and risks of rivaroxaban plus aspirin vary in patients with comorbidities and receiving multiple drugs. In patients with coronary or peripheral artery disease, adding low-dose rivaroxaban to aspirin reduces cardiovascular events and mortality. Polypharmacy and multimorbidity are frequent in such patients. METHODS AND RESULTS: We describe ischaemic events (cardiovascular death, stroke, or myocardial …

Authors

Vanassche T; Verhamme P; Anand SS; Shestakovska O; Leong DP; Fox KAA; Bhatt DL; Avezum A; Alings M; Aboyans V

Journal

European Heart Journal - Cardiovascular Pharmacotherapy, Vol. 8, No. 5, pp. 462–473

Publisher

Oxford University Press (OUP)

Publication Date

August 11, 2022

DOI

10.1093/ehjcvp/pvab050

ISSN

2055-6837