Chapter 17 Flow-Cytometric Identification and Characterization of Neural Brain Tumor-Initiating Cells for Pathophysiological Study and Biomedical Applications

Flow cytometry has garnered wide acceptance as an efficient tool for the isolation and enrichment of specific subpopulations of cells. Its utility in identifying brain tumor-initiating cells (BTICs) through their unique surface antigen expression is of particular interest in the fields of stem cell and cancer stem cell biology. Here, we review key cell-surface markers, like CD133, that are commonly used for isolating neural BTICs associated …