Chapter
Chapter 3 Pluripotent Stem Cell Microenvironment
Abstract
During generation of pluripotent epiblast within the mammalian preimplantation embryo, specification of extraembryonic lineages such as trophectoderm (TE) and primitive endoderm (PrE) is proceeding at the same time. Pluripotent cells appear to be mutually interacting with these neighboring extraembryonic cells that are dynamically changing in a short period of time relative to somatic stem cells. Indeed, environmental cues provided by TE and …
Authors
Nakanishi M; Bhatia M
Book title
Biology and Engineering of Stem Cell Niches
Pagination
pp. 33-49
Publisher
Elsevier
Publication Date
2017
DOI
10.1016/b978-0-12-802734-9.00003-2