Hypoxia regulated expression of erythropoietin in cultured myoblasts and myotubes (1102.35)

Erythropoietin (EPO) is responsible for supporting the growth and development of red blood cells. EPO is produced mainly by the kidney and its expression is regulated by hypoxia. Several studies have assessed the ability of skeletal muscle to produce EPO, using whole muscle biopsies, and have observed conflicting results. Here, cell culture, RT‐PCR, and flow cytometry were used. The objective was to determine if myoblasts and myotubes were …