Journal article
Thrombolytic Agents: Thrombosis‐Responsive Thrombolytic Coating Based on Thrombin‐Degradable Tissue Plasminogen Activator (t‐PA) Nanocapsules (Adv. Funct. Mater. 45/2017)
Abstract
In article number 1703934, Dan Li, Hong Chen, and co‐workers report a novel thrombolytic coating whose activity is triggered by thrombosis. The coated surfaces remain inert in normal plasma environment while releasing tissue plasminogen activator (t‐PA) and promoting fibrinolysis in response to thrombin. Such coating could avoid unfavorable complications caused by continuous release of antithrombotic agents.
Authors
Li C; Du H; Yang A; Jiang S; Li Z; Li D; Brash JL; Chen H
Journal
Advanced Functional Materials, Vol. 27, No. 45,
Publisher
Wiley
Publication Date
12 2017
DOI
10.1002/adfm.201770271
ISSN
1616-301X