Feasible Fabrication of Hollow Micro-vesicles by Non-amphiphilic Macromolecules Based on Interfacial Cononsolvency

Herein we present a new perspective showing that water-soluble liquids, when added to water, undergo transient emulsification before complete dissolution. Thus, non-amphiphilic macromolecules can self-assemble at the two-miscible-phase interface when cononsolvent effect appears. A representative case shown here is that when poly(N-isopropylacrylamide) (PNIPAm), prepared by aqueous radical polymerization, in methanol solution is added into …