An Approach to the Office-Based Practice of Food Oral Immunotherapy Academic Article uri icon

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  • Oral immunotherapy (OIT) provides an active treatment option for patients with food allergies. OIT may improve quality of life and raise the threshold at which a patient with food allergy may react to an allergen, but it is a rigorous therapy that requires a high degree of commitment by the clinician, patients, and families. Recent guidelines from the Canadian Society for Allergy and Clinical Immunology have provided a framework for the ethical, evidence-based, and patient-oriented clinical practice of OIT, and the European Academy of Allergy, Asthma, and Immunology guidelines have also recommended that OIT can be used as a potential treatment. The recent Food and Drug Administration approval of an OIT pharmaceutical has accelerated the adoption of OIT. This review provides a summary of the recent Canadian Society for Allergy and Clinical Immunology guidelines and a consensus of practical experience of clinicians across the United States and Canada related to patient selection, office and staff preparation, the general OIT process, OIT-related reaction management, and treatment outcomes.


  • Wasserman, Richard L
  • Factor, Jeffrey
  • Windom, Hugh H
  • Abrams, Elissa M
  • Begin, Philippe
  • Chan, Edmond S
  • Greenhawt, Matthew
  • Hare, Nathan
  • Mack, Douglas
  • Mansfield, Lyndon
  • Ben-Shoshan, Moshe
  • Stukus, David R
  • Leek, Timothy Vander
  • Shaker, Marcus

publication date

  • May 2021