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The Role of Denosumab for Surgical Outcomes in...
Journal article

The Role of Denosumab for Surgical Outcomes in Patients with Giant Cell Tumour of Bone: A Systematic Review

Abstract

Background: The role of denosumab in patients with resectable giant cell tumour of bone remains unclear. We asked the following research question: for patients (aged ≥ 12 years) with resectable giant cell tumour of bone, what are the benefits and harms of denosumab compared with no denosumab in terms of (1) facilitation of surgery (operative time, blood loss), (2) disease recurrence, (3) pain control, (4) disease stability, and (5) adverse …

Authors

Gupta A; Durocher-Allen L; Popovic S; Tozer R; Yao X; Ghert M

Journal

Current Oncology, Vol. 28, No. 2, pp. 1302–1313

Publisher

MDPI

DOI

10.3390/curroncol28020124

ISSN

1198-0052