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Taurine Release by Astrocytes Modulates...
Journal article

Taurine Release by Astrocytes Modulates Osmosensitive Glycine Receptor Tone and Excitability in the Adult Supraoptic Nucleus

Abstract

Cells can release the free amino acid taurine through volume-regulated anion channels (VRACs), and it has been hypothesized that taurine released from glial cells is capable of inhibiting action potential (AP) firing by activating neuronal glycine receptors (GlyRs) (Hussy et al., 1997). Although an inhibitory GlyR tone is widely observed in the brain, it remains unknown whether this specifically reflects gliotransmission because most neurons …

Authors

Choe KY; Olson JE; Bourque CW

Journal

Journal of Neuroscience, Vol. 32, No. 36, pp. 12518–12527

Publisher

Society for Neuroscience

Publication Date

September 5, 2012

DOI

10.1523/jneurosci.1380-12.2012

ISSN

0270-6474